Immune Modulation

Beneficial for Comprehensive Immune Modulation of the Body

Sometimes, stress is an unavoidable aspect of life. Unhealthy lifestyles such as social or work drinking, sleeping late, or nutritional imbalance can cause a weak immune system. When our bodies suffer from imbalanced or decreased immune systems, many issues such as disease or infection may occur.

Antromax™ can improve your immune response, meaning you’ll be able to better fight off viruses, bacteria, inflammation reactions, autoimmune attacks, or other diseases (such as cancer, hepatitis, or diabetes).

In summary, many studies have proven that A. cinnamomea has the potential for the following advantages to immune systems:

1.Stop virus replication

Inhibit ACE2 (Angiotensin-converting enzyme 2)1 and viral protease2, which can suppress viral replication

2.Enhance fighting power

Increase the number of T cells, helper T cells, killer T cells, B cells, and natural killer cells

3.Non-specific immunity (innate immunity) – immediate defense

Increase the content of cytokines IL-2 and IFN-γ

4.Specific immunity (adaptive immunity) – precision attacks

Increase the content of antibodies IgG and IgM

5.Immunity protection

Prevent severe inflammatory reactions caused by overly active immune systems3, reduce lung infiltration and tissue damage caused by pneumonia4, reduce the occurrence of pulmonary fibrosis5

Can Increase the Number of T and B Cells in the Spleen

CD8+ are killer T cells which can be significantly increased to enhance their ability to kill pathogens.
CD4+ are helper T cells that can act as information soldiers by secreting cytokines that alarm other immune cells to attack.

Can Increase the Content of Cytokines IL-2 and IFN-γ

In the absence of stimulus, T cells on standby are not prompted to emit cytokines at will, leaving other immune cells in a state of tension.
When stimulus is introduced, Antromax™ increases T cell secretion of more cytokines to quickly alarm more immune cells to fight.

Can increase the Content of Antibodies IgG and IgM

When stimulus (OVA) is introduced, Antromax™ can utilize B cells to create more antibodies so that the body has sufficient ammunition to eliminate germs.

References

1 A. Carino et al. Hijacking SARS-CoV-2/ACE2 receptor interaction by natural and semi-synthetic steroidal agents acting on functional pockets on the receptor binding domain. Front Chem. (2020) 8: 572885.
2 D.T. Phuong et al. Inhibitory effects of antrodins A-E from Antrodia cinnamomea and their metabolites on hepatitis C virus protease. Phytother Res. (2009) 23: 582-4.
3 L. M. Meng. Immunoregulatory effects of polysaccharides from Antrodia camphorata in sepsis and pulmonary inflammation. (2012) Taipei medical university.
4 Huang et al. Methanol extract of Antrodia camphorata protects against lipopolysaccharide-induced acute lung injury by suppressing NF-κB and MAPK pathways in mice. J Agric Food Chem. (2014) 62: 5321-9.
5 Lan et al. The therapeutic effect of Antrodia cinnamomea on bleomycin-induced pulmonary fibrosis in mice. Am J Respir Crit Care Med. (2012) 185: A1946.